Neural pathway key to sensation of pleasant touch identified (Links to an external site)

Zhou-Feng Chen, PhD, director of the Center for the Study of Itch & Sensory Disorders at Washington University School of Medicine in St. Louis, alongside his team, identified a neural circuit and a neuropeptide in mice — a chemical messenger that carries signals between nerve cells — that transmit the sensation known as pleasant touch from the skin to the brain.

Scratching an itch

A new mechanism involved in the sensation of itching has been found in mice.

A neuropeptide code for itch (Links to an external site)

The encoding of itch by peripheral and central neural circuits is a topic of long-standing interest in the somatosensory field. Here, Zhou-Feng Chen outlines a model for itch coding that emphasizes the role of neuropeptides in conveying itch information from the periphery to the spinal cord.

What makes us sneeze? (Links to an external site)

A team led by researchers at Washington University School of Medicine in St. Louis has identified, in mice, specific cells and proteins that control the sneeze reflex. Better understanding of what causes us to sneeze — specifically how neurons behave in response to allergens and viruses — may point to treatments capable of slowing the spread of infectious respiratory diseases.

What makes the aging skin itchy?

Congratulation to Dr. Hongzhen Hu!  A new study explains why getting old may make you itchy.  Read news Record, Science, Live Science, UPI, Science Alert, PainWeek, people.cn.

Potential new therapy relieves chronic itch

Congratulations to Dr. Brian Kim’s team! Dr. Brian Kim, dermatologist, and Landon Oetjen, MD/PhD student, of the CSI discover highly promising new pathway for the treatment of chronic itch. Please read news Record, Daily Mail.

Why itch is contagious?

Dr. Zhou-Feng Chen’s team discovers why mice scratch in response to other mice scratching. Read news Record, St.Louis Public Radio, Independent, NBC, Daily Mail, The Guardian, Hoffington Post, Smithsonian, Express, Livescience, Inverse, Cell, 知识分子. Watch video here: Scientific American.

New York Times Features Innovative Research at CSI from The New York Times

In a recent interview with The New York Times, Drs. Zhou-Feng Chen and Lynn Cornelius, talk about chronic itch as an unmet need and the clinical implication of the discovery of an itch-specific receptor called GRPR. Read The New York Time article “Itching: more than deep-skin”.

BBC interview: Itchy and Scratchy

“What is an itch and how does scratching stop it? Why does scratching some itches feel so good?!” asks Xander Tarver from Wisborough Green in West Sussex. Our doctors set off to probe the mysteries of itch, and discover that this overlooked area of medicine is revealing surprising results about the human brain. From why itching […]