The Center for the Study of Itch & Sensory Disorders seeks to understand the fundamental underlying mechanisms of itch and translate these findings into treatments for patients suffering from intractable itch.


How is innocuous light touch converted into itch?

A new study, from Dr. Zhou-Feng Chen’s team, reveals a novel neural circuit that converts innocuous light touch into an irritating itch sensation. Tac2 neurons receive light touch information and convey it to GRPR neurons, which convert it into irritating itch.

GRP fibers in the skin are itch specific

Using novel genetic tools, Dr. Zhou-Feng Chen’s team has demonstrated the role of GRP in nonhistaminergic itch in sensory neurons and GRP primary afferents are dedicated to the itch transmission.

Revving up immune system may help treat eczema

Brian S. Kim, MD, has found that boosting the number of natural killer cells in the blood is a possible treatment strategy for the skin condition, eczema, and also may help with related health problems, such as asthma.

What makes the aging skin itchy?

Congratulation to Dr. Hongzhen Hu!  A new study explains why getting old may make you itchy.  Read news Record, Science, Live Science, UPI, Science Alert, PainWeek,

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