The Center for the Study of Itch & Sensory Disorders seeks to understand the fundamental underlying mechanisms of itch and translate these findings into treatments for patients suffering from intractable itch.

The Center is composed of two major academic programs: Basic and Translational Research and Behavioral Core and Patient Care, Clinical Studies and Clinical Trials. Learn more about the Center.


 

Trpv4-eGFP ear skin V4 Avidin (red): Trpv4 Expression in the skin

Trpv4-eGFP ear skin V4 F480 (red): Trpv4 Expression in the skin


OXT, Cre, GFP Triple Staining

Dorsal Root Ganglion: Gastrin-releasing peptide (GRP, red), an itch-specific neurotransmitter, is not coexpressed with NF200 (green), a marker for myelinated fibers in the dorsal root ganglion (DRG) cells.

 

News

GRP fibers in the skin are itch specific

Using novel genetic tools, Dr. Zhou-Feng Chen’s team has demonstrated the role of GRP in nonhistaminergic itch in sensory neurons and GRP primary afferents are dedicated to the itch transmission.

Revving up immune system may help treat eczema

Brian S. Kim, MD, has found that boosting the number of natural killer cells in the blood is a possible treatment strategy for the skin condition, eczema, and also may help with related health problems, such as asthma.

What makes the aging skin itchy?

Congratulation to Dr. Hongzhen Hu!  A new study explains why getting old may make you itchy.  Read news Record, Science, Live Science, UPI, Science Alert, PainWeek, people.cn.

Potential new therapy relieves chronic itch

Congratulations to Dr. Brian Kim's team! Dr. Brian Kim, dermatologist, and Landon Oetjen, MD/PhD student, of the CSI discover highly promising new pathway for the treatment of chronic itch. Please read news Record, Daily Mail.

Recent Publications